Despite their high incidence and debilitating effects, chronic pain
syndromes remain largely untreatable. Neck pain comprises nearly 30% of
all chronic pain syndromes and is equally problematic. However, neck
pain currently remains largely unstudied, with only inferential
hypotheses for its etiology. Research efforts in the Spine Pain
Research Laboratory examine the pathomechanisms of chronic neck pain,
by studying the two most common forms of injuries to the cervical spine
and using these to determine the cellular/molecular factors that lead
to chronic pain for each injury. Research is broadly focused on
understanding how precise mechanical loading - mimicking clinically
relevant conditions of pain - translates to physiologic processes of
persistent neck pain. Spinal neuroimmunologic cascades are prime
candidates for causing a chronic pain response, with specific interest
on defining the spinal cytokine and glial changes of pain.
Investigations have the potential to provide new insight into the
mechanism(s) for persistent pain and identify the key regulators in
cervical spine-based pain, with the ultimate goal of translating
molecular understandings of pain to its clinically effective treatment.
Position Available Immediately: Postdoctoral Fellow